IHC-plus™ HPSE / Heparanase Antibody LS-B2441 | LifeSpan Biosciences LS-B2441 product information

product summary

company name :

LifeSpan Biosciences

product type :

antibody

product name :

IHC-plus™ HPSE / Heparanase Antibody LS-B2441

catalog :

LS-B2441

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

LifeSpan Biosciences product webpage

citations: 1

Reference
Spyrou A, Kundu S, Haseeb L, Yu D, Olofsson T, Dredge K, et al. Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth. Mol Cancer Ther. 2017;16:1705-1716 pubmed publisher

image

image 1 :

Anti-Heparanase antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

product information

AntibodyID :

83784

AntibodyName :

LS-B2441

TargetSpecies :

Human

Host Species :

Rabbit

Product Name :

IHC-plus™ HPSE / Heparanase Antibody LS-B2441

Specificity :

Recognizes the 65kD precursor as well as the 50kD and 8kD subunits of human or mouse Heparanase.

ClonalityDesc :

Polyclonal

AntibodyModification :

Unconjugated

PresentationDesc :

PBS, pH 7.2, 0.01% Thimerosal

ImmunogenType :

Recombinant protein

ImmunogenDesc :

A heterodimeric recombinant protein consisting of the 50 kDa and 8 kDa subunits.

PurificationDesc :

Protein G purified

RecommendedStorageDesc :

Short term: 4°C Long term: Aliquot and store at -20°C. Avoid freeze-thaw cycles.

IsotypeName :

IgG

Gene :

HPSE / Heparanase

StandardGeneSymbol :

HPSE

Reactivity :

Mouse, Human

Usage :

IHC, IHC-P (5 µg/ml), WB (1:2000)

ShortWebDescription :

Heparanase antibody LS-B2441 is an unconjugated rabbit polyclonal antibody to Heparanase (HPSE) from human. It is reactive with human and mouse. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.

UsageText :

Immunohistochemistry: LS-B2441 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2441 was determined to be 5 ug/ml. Western Blot: 1:1000.

Synonyms :

HPSE, Endo-glucoronidase, Heparanase-1, Heparanase, HPA, HSE1, HEP, HPA1, HPSE1, HPR1

SalesRegion :

Worldwide

more info or order :

LifeSpan Biosciences product webpage

company information

LifeSpan Biosciences

2401 Fourth Avenue, Suite 900
Seattle, WA 98121

CustomerSupport@lsbio.com

https://www.lsbio.com

1-206-464-1554

headquarters: USA

Since 1995, LifeSpan has been the industry leader in molecular pathology, specializing in the localization of proteins in normal and diseased tissues, both human and non-human. We offer more than 74,000 antibodies, custom designed immunohistochemistry (IHC) studies, immediately available human tissue IHC profiles for more than 500 proteins, and histology and pathology services. Our bank of 2 million specimens is available to support our customers' contract research studies and contains frozen and formalin-fixed (FFPE) normal and diseased tissues. Our contract services are comprehensive; they include study design, antibody sourcing and characterization, tissue sourcing and validation, immunolabeling, trouble shooting, and interpretation of the results by a LifeSpan pathologist.