Rabbit AntiGABAA receptor alpha 1 | ImmuQuest IQ226 product information

product summary

request information :

company name :

ImmuQuest

product type :

antibody

product name :

Rabbit AntiGABAA receptor alpha 1

catalog :

IQ226

quantity :

0.5 ml (0.2 mg/ml)

price :

299 USD

clonality :

monoclonal

host :

mouse

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

ImmuQuest product webpage

product information

Target Antigen :

GABAA receptor alpha 1

Primary Description :

Rabbit AntiGABAA receptor alpha 1

Catalgoue Number :

IQ226

quantity :

0.5 ml (0.2 mg/ml)

Host/Isotype :

rabbit

Immunogen :

Thyroglobulincoupled peptide corresponding to aminoacids 114 (QPSQDELKDNTTVFC) of GABAA receptor a1 subunit. The Cys residue was added for directional coupling to the carrier protein

Specificity :

Reacts with GABAA receptor in mouse rat, and it should work for human bovine. Does not crossreact with any other GABAA receptor subunit ;

Purification :

Affinity purified on a peptide immunogenaffinity

Format :

Affinity purified antiserum containing PBS 0.1% sodium azide;

Applications :

IB; ICC;

Dilutions :

Optimal antibody dilution should be determined by titration, however as a guideline try 0.250.5 g/ml for immunoblots 0.2 g/ml for immunohistochemistry

Relevance :

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at Gamma aminobutyric acid type A (GABA A) receptors. GABA A receptors are ligand gated chloride ion channels. These receptors are believed to be pentameric hetero oligomers, for which 6 subunits are currently known (alpha, beta, gamma, delta, epsilon and rho). GABA A receptors mediate the majority of fast inhibitor synaptic transmissions in the brain. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA A receptor.

References :

Developmental regulation of expression of GABAA receptor alpha 1 and alpha 6 subunits in cultured rat cerebellar granule cells Thompso CL ( Neuropharmacology,1996)

Research areas :

GABA; Neuroscience;

Also known as :

EJM antibody;Gaba receptor alpha 1 polypeptide antibody;GABA(A) receptor subunit alpha1 antibody;GABRA 1 antibody;GABRA1 antibody;Gamma aminobutyric acid (GABA) A receptor alpha 1 antibody;Gammaaminobutyric acid A receptor alpha 1 antibody;Gamma aminobutyric acid receptor subunit alpha 1antibody

Price (Pounds) :

226

Price (Dollars) :

299 USD

Price (Euros) :

338

more info or order :

ImmuQuest product webpage