product summary
Loading...
company name :
ImmuQuest
product type :
antibody
product name :
hnRNP K antibody [3C2]
catalog :
IQ213
quantity :
0.1 ml
price :
299 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3C2
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunocytochemistry, flow cytometry
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human
Gao R, Yu Y, Inoue A, Widodo N, Kaul S, Wadhwa R. Heterogeneous nuclear ribonucleoprotein K (hnRNP-K) promotes tumor metastasis by induction of genes involved in extracellular matrix, cell movement, and angiogenesis. J Biol Chem. 2013;288:15046-56 pubmed publisher
Marchand V, Santerre M, Aigueperse C, Fouillen L, Saliou J, Van Dorsselaer A, et al. Identification of protein partners of the human immunodeficiency virus 1 tat/rev exon 3 leads to the discovery of a new HIV-1 splicing regulator, protein hnRNP K. RNA Biol. 2011;8:325-42 pubmed
Chang J, Koike T, Iwashima M. hnRNP-K is a nuclear target of TCR-activated ERK and required for T-cell late activation. Int Immunol. 2009;21:1351-61 pubmed publisher
Enge M, Bao W, Hedström E, Jackson S, Moumen A, Selivanova G. MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53. Cancer Cell. 2009;15:171-83 pubmed publisher
Fukuda T, Naiki T, Saito M, Irie K. hnRNP K interacts with RNA binding motif protein 42 and functions in the maintenance of cellular ATP level during stress conditions. Genes Cells. 2009;14:113-28 pubmed publisher
Schulz M, Dotzlaw H, Mikkat S, Eggert M, Neeck G. Proteomic analysis of peripheral blood mononuclear cells: selective protein processing observed in patients with rheumatoid arthritis. J Proteome Res. 2007;6:3752-9 pubmed
Guil S, Caceres J. The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a. Nat Struct Mol Biol. 2007;14:591-6 pubmed
Inoue A, Sawata S, Taira K, Wadhwa R. Loss-of-function screening by randomized intracellular antibodies: identification of hnRNP-K as a potential target for metastasis. Proc Natl Acad Sci U S A. 2007;104:8983-8 pubmed
Griffith B, Walsh C, Szeszel Fedorowicz W, Timperman A, Salati L. Identification of hnRNPs K, L and A2/B1 as candidate proteins involved in the nutritional regulation of mRNA splicing. Biochim Biophys Acta. 2006;1759:552-61 pubmed
Szeszel Fedorowicz W, Talukdar I, Griffith B, Walsh C, Salati L. An exonic splicing silencer is involved in the regulated splicing of glucose 6-phosphate dehydrogenase mRNA. J Biol Chem. 2006;281:34146-58 pubmed
Blanchette A, Fuentes Medel Y, Gardner P. Cell-type-specific and developmental regulation of heterogeneous nuclear ribonucleoprotein K mRNA in the rat nervous system. Gene Expr Patterns. 2006;6:596-606 pubmed
Yano M, Okano H, Okano H. Involvement of Hu and heterogeneous nuclear ribonucleoprotein K in neuronal differentiation through p21 mRNA post-transcriptional regulation. J Biol Chem. 2005;280:12690-9 pubmed
product information
Product Name :
hnRNP K antibody [3C2]
Target Antigen :
hnRNP K 
Primary Description :
Mouse Anti-hnRNP K [3C2]
Catalogue Number :
IQ213
Quantity :
0.1 ml
Concentration :
1mg/ml
Clone :
3C2
Host :
Mouse 
Isotype :
IgG2b
Immunogen :
Full length native protein (purified) (Human)
Myeloma/fusion partners :
SP2/0
Species Reactivity :
Mouse, Rat, Hamster, Cow, Human, Xenopus laevis
Purification :
protein A
Format :
Purified antibody (from supernatant) containing PBS 0.1% sodium azide;
Applications :
ELISA, WB, ICC/IF, Flow Cyt
Dilutions :
Optimal antibody dilution should be determined by titration, however as a guideline try;WB: 1/1000. Detects a band of approximately 65 kDa (predicted molecular weight: 51 kDa)Flow Cyt: Use 1µg for 106 cellsChIP/Chip: Use at an assay dependent dilution. PubMed: 20673990
Also known as :
CSBP antibody;dC stretch binding protein antibody;FLJ41122 antibody;Heterogeneous nuclearribonucleoprotein K antibody;hnRNP K antibody;HNRNPK antibody;HNRPK antibody;HNRPK_HUMANantibody;Transformation up regulated nuclear antibody;Transformation up regulated nuclear proteinantibody;Transformation up-regulated nuclear protein antibody;Transformation upregulated nuclear proteinantibody;TUNP antibody
List Price (Pounds) :
299 USD
Pubmed ID :
li, sprague, tang, zhao, jansz, sun, booy, thompson, chen, ghosh, grassilli, fan, marques, giraud, porro, tsai, huarte, 30736860, 31097619, 30372559, 30942456, 30428357, 29311158, 30174313, 30247708, 29921878, 27862976, 28232485, 28324005, 26804170, 25611934, 26330540, 25401475, 24113282, 24434558, 24529708, 23825951, 20673990, 23564449, 21368586, 19880579, 19249676, 19170760, 17705417, 17558416, 17483488, 16488668, 17095106, 16980303, 15671036, 2931115
SwissProt ID :
q3t0d0, p61978, p61980, P61978, P61979, P61980
more info or order :
company information
ImmuQuest
26 The Green
Seamer, N.Yorkshire
TS9 5LP
adam@immuquest.com
https://www.immuquest.com/
44 0 1642-713533
headquarters: UK
Our QUEST is to work in partnership with the scientific community to deliver a unique and, wherever possible, exclusive range of quality antibodies for use in existing and emerging areas of scientific research.