This web page lists suppliers providing gene knockdown. The knockdown reagents include siRNA, shRNA, antisense oligos such as morpholino antisense oligos, and gene editing reagents for CRISPR, TALENs, Zinc fingers, and meganucleases. Due to the large number of potential products, the suppliers usually provide custom-made products, instead of catalog products. Morpholinos, like antisense vivo-morpholino oligonucleotides [1], are usually provided by Gene Tools [2].

The list is compiled from a systematic manual survey conducted by Labome covering over 60000 randomly selected publications (read how Labome selects the articles). This list includes suppliers whose products have been cited in at least one publications. Up to five most cited products for each supplier are displayed. Therefore, this list provides a comprehensive representation of high-quality suppliers in this product category. A small number of high-quality suppliers without any citation may also be included; they are not accompanied by any citation data. As the Labome survey is ongoing, this list is updated regularly to reflect the most recent data. Please note: a few companies have been purchased by or merged with other companies, they remain on the list if their brands are maintained by the new entities, such as Life Technologies, Sigma-Aldrich.

The total number of citations for gene knockdown is 3807 from 2595 publications.

2145 Delaware Avenue
Santa Cruz, CA 95060

scbt@scbt.com

https://www.scbt.com

1.800.457.3801

headquarters: USA

Most cited: Control shRNA Lentiviral Particles-A, siRNA Transfection Reagent, p53 siRNA (h), AMPKalpha1/2 siRNA (h), BECN1 siRNA (h).

Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451

https://www.thermofisher.com

800-678-5599

headquarters: USA

9620 Medical Center Drive
Rockville, MD 20850

inquiry@genecopoeia.com

https://www.genecopoeia.com

1-301-762-0888

headquarters: USA

GeneCopoeia offers the largest collection of expression-ready ORF cDNA, shRNA and miRNA clones. Available in a wide collection of lentiviral and non-viral expression vectors with a variety of fusion tags and reporters including fluorescent, solubility, purification and multi-functional tags. Explore the fully sequenced and expression-ready clone collections here.

Most cited: Human APC2 shRNA clone set, viral or non-viral, Human TRIOBP shRNA clone set, viral or non-viral, Human EGFR shRNA clone set, viral or non-viral, Human EP300 shRNA clone set, viral or non-viral, Human FOXO3 shRNA clone set, viral or non-viral.

9th Fl., No.108, Jhouzih St.
Neihu District. Taipei City
114 Taiwan

sales@abnova.com

https://www.abnova.com

877-853-6098

Most cited: RNA Marker Low, CCNE1/CEN19p FISH Probe, MADH4(Texas Red)/CEN18q(FITC) FISH Probe, CEN11p (FITC) FISH Probe, CHOP Split FISH Probe.

9620 Medical Center Dr., Suite 200
Rockville, MD 20850

custsupport@origene.com

https://www.origene.com

1-888-267-4436

headquarters: USA

OriGene Technologies, Inc. is a gene centric life sciences company dedicated to support biomedical scientists in gene functions and drug discovery. OriGene’s novel product line includes the world’s largest collections of cDNA clones (TrueClone and TrueORF), shRNA (HuSH-29), purified human recombinant proteins, high quality TrueMAB™ monoclonal antibodies to human proteins, 100,000 highly validated human tissues, and qPCR arrays. OriGene also provides a broad range of antibody validation products including genome-wide tagged antigen standards and extensive IHC slides derived from our tissue collection. OriGene is a Luminex Certified Partner™ and offers multiplexed immunoassays and multiplexed assays for a broad range of biomarkers.

P.O. Box 153308
San Diego, CA 92195-3308

sales@mybiosource.com

https://www.mybiosource.com

1-888-627-0165

headquarters: USA

MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

Cited: siRNA Negative Control.

Lochhamer Straße 29a
82152 Planegg / Martinsried

info@sitools.de

http://www.sitoolsbiotech.com

49 (0) 89 12501 4800

headquarters: Germany

Cited: TP53 siPOOL (human).

8999 BioLegend Way
San Diego, CA 92121

customerserv@biolegend.com

https://www.biolegend.com

headquarters: USA

614 McKinley Place N.E.
Minneapolis, MN 55413

info@RnDSystems.com

https://www.rndsystems.com

800 343-7475

headquarters: USA

R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.

10771 E Easter Ave
Centennial, CO 80112

novus@novusbio.com

https://www.novusbio.com

3037301950

headquarters: USA

Novus Biologicals licenses, manufactures, and markets antibodies to over 20,000 unique targets to support a wide array of research areas. Novus is built on honesty, collaboration and strong relationships and continues to provide quality tools that accelerate research. Every product is backed by our 100% guarantee.

NY, USA

contact@creative-biomart.com

http://www.creativebiomart.net

1-516-855-7709

headquarters: USA

Creative BioMart provides quality recombinant proteins, diagnostic antibodies and antigens, diagnostic enzymes and pharmaceutical enzymes to the research community of biology, clinical research, molecular diagnostics and biopharmaceutical drug development.

cs-us@ge.com

http://www.gelifesciences.com

3 Trask Lane
Danvers, MA 01923

info@cellsignal.com

https://www.cellsignal.com

8776162355

headquarters: USA

Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.

Most cited: SignalSilence® Control siRNA (Unconjugated), SignalSilence® Akt siRNA I, SignalSilence® Control siRNA (Fluorescein Conjugate), SignalSilence® ERK5 siRNA I, SignalSilence® Ezh2 siRNA I.

informatics.usa@bio-rad.com

http://www.bio-rad.com

contact_us@agilent.com

http://www.Agilent.com

160 Oxmoor Blvd
Birmingham, AL 35209

info@SouthernBiotech.com

http://www.southernbiotech.com

205-945-1774

headquarters: USA

Southern Biotechnology Associates, Inc., now known as SouthernBiotech, was founded in 1982 as a company dedicated to the production, purification, conjugation and commercialization of the world's highest quality, affinity purified, secondary antibodies for research use. As a result of ongoing internal product development and our acquisition of monoclonal antibody producing cell lines through technology transfer arrangements with leading research universities and institutions, we now provide a broad range of affinity purified, polyclonal and monoclonal antibodies, including, fluorochrome and enzyme conjugates, Low Endotoxin/Azide Free (LE/AF) preparations, F(ab) and F(ab')2 fragments, as well as, purified immunoglobulins and collagens.

980 Linda Vista Avenue
Mountain View, California 94043

support@biovision.com

http://www.biovision.com

1-650-428-0236

headquarters: USA

BioVision, Inc., a privately held company headquartered in the beautiful San Francisco Bay area, specializes in developing and manufacturing research products for molecular and cell biologists. BioVision offers a wide variety of products including reagents, bioassay kits, antibodies, recombinant proteins, and other research tools for studying apoptosis, cell signaling pathways, cell proliferation, metabolism, cellular stress, cell damage and repair, cholesterol and obesity, Protein A/G/L, multi-color fluorescence proteins and gene regulation, etc. BioVision’s products are currently being sold in more than 60 countries worldwide.

2626 South Loop West, Suite 225
Houston, TX 77054

enquiry@selleckchem.com

http://www.selleckchem.com

877 796-6397

headquarters: USA

PO Box 14508
St. Louis, MO 63178

https://www.sigmaaldrich.com

1-800-325-3010

headquarters: USA

490 Arsenal Way, Suite 100
Watertown, MA 02472

info@addgene.org

https://www.addgene.org

617.225.9000

headquarters: USA

15A Constitution Way Woburn, MA 01801

customerservice@mblintl.com

http://www.mblintl.com

headquarters: United States