beta 2 Microglobulin antibody | knockout validation | Abcam ab75853

This is a knockout-validated antibody summary, based on the publication "CD4+ T cells induce rejection of urothelial tumors after immune checkpoint blockade", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Antibody information

Rabbit monoclonal IgG

Company: Abcam

Antibody: beta 2 Microglobulin

Catalog number: ab75853

Summary: Rabbit monoclonal IgG against a synthetic peptide within human beta 2 Microglobulin (C terminal). Reacts with: mouse, rat, and human. Suitable for western blot, immunocytochemistry/immunofluorescence, immunoprecipitation, and flow cytometry. Unsuitable for immunohistochemistry (paraffin).

Validation Method

Western blot

Sample

WT and B2m-KO MCB6C cell tumors.

Figure

B2m expression, as shown by Western blot, of MCB6C using B2m-KO clones grown in vitro. Please see Figure 4b in the article [1].

References
  1. Sato Y, Bolzenius J, Eteleeb A, Su X, Maher C, Sehn J, et al. CD4+ T cells induce rejection of urothelial tumors after immune checkpoint blockade. JCI Insight. 2018;3: pubmed publisher