This is a knockout-validated antibody summary, based on the publication "Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

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Figure 1. Western blot of lysates of XIAP knockout MEFs and knockout MEFs transfected with constructs expressing wild-type (WT) or mutant (H647A) XIAP. Blots were probed with anti-XIAP antibody. Actin serves as a loading control. From Figure 3 in [1].

Mouse monoclonal

Company: BD Bioscience

Antibody: XIAP

Catalog number: 610763

Summary: Mouse monoclonal antibody raised against a polypeptide corresponding to residues 268-426 of human XIAP. Supplier recommended for WB, IHC and IF. Reacts with human, rat, mouse and frog XIAP.

Western blot

Lysates of XIAP knockout MEFs or the knockout MEFs transfected with plasmid expressing wild-type or mutant XIAP.

Anti-XIAP antibody.

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.