WDR68 antibody | knockout validation | Abcam ab138490

This is a knockout-validated antibody summary, based on the publication "A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

WDR68 antibody | knockout validation | Abcam ab138490 figure 1
Figure 1. WT 293T or the 293T-based DCAF7 KO clones were analyzed by WB. From [1].
Antibody information

Rabbit monoclonal IgG

Company: Abcam

Antibody: WDR68

Catalog number: ab138490

Summary: Rabbit monoclonal IgG against a synthetic peptide within human WDR68 (aa 200-300). Reacts with mouse, rat, and human. Suitable for western blot, immunohistochemistry (paraffin), immunocytochemistry/immunofluorescence, and flow cytometry. Unsuitable for immunoprecipitation.

Validation Method

Western blot

Sample

WT and DCAF7 KO 293T cells.

References
  1. Yu D, Cattoglio C, Xue Y, Zhou Q. A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis. Nucleic Acids Res. 2019;47:4462-4475 pubmed publisher