This is a knockout-validated antibody summary, based on the publication "A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).
Mouse monoclonal IgG2a (kappa light chain)
Company: Santa Cruz
Antibody: WASP
Catalog number: sc-365859
Summary: Mouse monoclonal antibody specific for an epitope mapping between amino acids 197-222 within an internal region of human WASP. Recommended for detection of WASP of mouse, rat and human by western blot, immunoprecipitation, immunofluorescence and ELISA. Also reactive with additional species, including canine.
Western blot
Peripheral blood T cell lysates from a healthy control and a WASpnull patient and mouse splenic T cells from WT and Was–/– mice.
Representative immunoblot of the indicated proteins in peripheral blood T cell lysates from a healthy control (HC) and a WASpnull patient (A) and of mouse splenic T cells from WT and Was–/– mice (B). Please see Figure 2a,b in the article [1].
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