This is a knockout-validated antibody summary, based on the publication "Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Figure 1. From Figure 1 in [1]. Primary oligodendrocyte precursor cells from wild-type and TSC1 knockout mice were stained using an anti-Tsc1 antibody. Bar indicates 10μm.

Goat polyclonal

Company: Pierce (ThermoFisher Scientific)

Antibody: Tsc1

Catalog number: PA5-18506

Summary: Goat polyclonal antibody raised against the peptide sequence QLHIMDYNETHHEH from the C-terminal region of Tsc1.

Supplier recommended for WB and IHC.

Reacts with human Tsc1.

Immunocytochemistry

Primary oligodendrocyte precursor cells from wild-type and TSC1 knockout mice.

Anti-Tsc1 antibody diluted 1:200.

Nikon E-C2 confocal microscope.

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.