This is a knockout-validated antibody summary, based on the publication "Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

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Figure 1. Representative images of immunocytochemistry staining of TG2 in the TG2 KO, SMAD3 KO and WT IPF fibroblasts. TG2 (green), Hoechst (blue). From [1].

Mouse monoclonal IgG1

Company: Abcam

Antibody: Transglutaminase 2

Catalog number: ab2386

Summary: Mouse monoclonal antibody against full length native protein (purified) corresponding to Transglutaminase 2. Reacts with mouse, rabbit, guinea pig, cat, dog, and human. Suitable for western blot, immunocytochemistry/immunofluorescence, immunohistochemistry (paraffin) and flow cytometry.

Immunocytochemistry

WT and TG2 KO idiopathic pulmonary fibrosis (IPF) fibroblasts.

The same clone (CUB 7402) is sold as LifeSpan Biosciences LS-C87955, LS-C87956, LS-B8560; Abcam ab2386; Invitrogen MA5-12736, MA5-12739.