Thermo Scientific monoclonal and Abcam rabbit polyclonal Trbp antibodies were validated in knockout mice
DOI
http://dx.doi.org/10.13070/ko.en.6.1579
Date
2016-08-29

This is a knockout-validated antibody summary, based on the publication "Trbp regulates heart function through microRNA-mediated Sox6 repression", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Company
Thermo Scientific

Antibody: Monoclonal anti Trbp

Catalogue No: LF-MA0209

Dilution :1:1000

Thermo Scientific monoclonal and Abcam rabbit polyclonal Trbp antibodies were validated in knockout mice figure 1
Figure 1. Trbp expression in wild-type and TrbpcKO mice.
Abcam

Antibody: Rabbit polyclonal Trbp

Catalogue No: ab42018. This antibody has been discontinued by Abcam.

Dilution :1:1000

Summary

The antibodies wwere validated in TrbpcKO mice by immunoblotting [1]. Trbp protein levels in the hearts of TrbpcKO and wild-type mice were assayed with Western blot.

Experimental design

Technique: WB

Sample: Heart tissue

Results

Trbp expression was not detected in TrbpcKO mice (see figure 1).

References
  1. Ding J, Chen J, Wang Y, Kataoka M, Ma L, Zhou P, et al. Trbp regulates heart function through microRNA-mediated Sox6 repression. Nat Genet. 2015;47:776-83 pubmed publisher