Tenascin C antibody | knockout validation | Cell Signaling 12221
This is a knockout-validated antibody summary, based on the publication "Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).
Figure 1. The effect of TNC knockout in 4T1-Atg5KO cells using CRISPR-Cas9 technology. From [1].
Antibody information
Rabbit monoclonal IgG
Company: Cell Signaling
Antibody: Tenascin C
Catalog number: 12221
Summary: Rabbit monoclonal antibody against a synthetic peptide corresponding to residues near the carboxy terminus of human Tenascin C protein. Reacts with human, mouse and rat. Suitable for western blot and immunoprecipitation.
Validation Method
Western blot
Sample
Control and TNC-KO Atg5-KO 4T1 cells.
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