This is a knockout-validated antibody summary, based on the publication "Intrinsic self-DNA triggers inflammatory disease dependent on STING", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Mouse monoclonal IgG1

Company: BD Biosciences

Antibody: TREX1

Catalog number: 611987

Summary: Mouse monoclonal IgG1 against mouse TREX1 aa. 82-179. Reacts with mouse by western blot. Not recommended for immunofluorescence.

Western blot

Heart lysates from WT, TREX1-KO, STING-KO, and STING/TREX1-DKO mice.

Please see Figure 1a in the article [1].

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.