TIMP2 antibody | knockout validation | Cell Signaling 5738

This is a knockout-validated antibody summary, based on the publication "Human umbilical cord plasma proteins revitalize hippocampal function in aged mice", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

TIMP2 antibody | knockout validation | Cell Signaling 5738 figure 1
Figure 1. TIMP2 immunoblot from equal volumes of 7- to 8-week-old or 20-month-old WT mouse plasma. From [1].
Antibody information

Rabbit monoclonal IgG

Company: Cell Signaling

Antibody: TIMP2

Catalog number: 5738

Summary: Rabbit monoclonal IgG against a synthetic peptide corresponding residues surrounding Thr135 of human TIMP2 protein. Reacts with human, mouse and monkey by western blot.

Validation Method

Western blot

Sample

Plasma from WT and TIMP2-KO mice.

Primary incubation

1:500 dilution.

References
  1. Castellano J, Mosher K, Abbey R, McBride A, James M, Berdnik D, et al. Human umbilical cord plasma proteins revitalize hippocampal function in aged mice.. Nature. 2017;544:488-492 pubmed publisher