TAK1 antibody | knockout validation

TAK1 antibody | knockout validation | R&D MAB5307

This is a knockout-validated antibody summary, based on the publication "A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Notes

This antibody referred in the article could also be #4505 from Cell Signaling.

Antibody information

Mouse monoclonal IgG1

Company: R&D

Antibody: TAK1

Catalog number: MAB5307

Summary: Mouse monoclonal IgG1 against recombinant human TAK1 isoform 1A (Met1-Ser579). Reacts with human by western blot.

Validation Method

Western blot

Sample

Parental, NIK−/− and TAK1−/− fibroblasts.

Figure

Western blot shows endogenous NIK and TAK1 expression in parental, NIK−/− and TAK1−/− cells. Please see Extended Data Fig. 1d in the article [1].

References

Liu Z, Mar K, Hanners N, Perelman S, Kanchwala M, Xing C, et al. A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. Nature. 2019;: pubmed publisher

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