This is a knockout-validated antibody summary, based on the publication "The GLP1R Agonist Liraglutide Reduces Hyperglucagonemia Induced by the SGLT2 Inhibitor Dapagliflozin via Somatostatin Release", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Figure 1. Representative images of immunofluorescence staining for SSTR2 in SSTR2 KO mice (top panel) and WT mice (bottom panel) performed on formalin-fixed, paraffin-embedded (FFPE) tissue sections (pancreatic islets). Scale bar 100 um. From [1].

Mouse monoclonal IgG1 κ

Company: Santa Cruz

Antibody: SSTR2

Catalog number: sc-365502

Summary: Mouse monoclonal IgG1 κ against amino acids 320-369 mapping at the C-terminus of human SSTR2a. Recommended for detection of SSTR2a of mouse, rat and human origin by western blot, immunoprecipitation, immunofluorescence, immunohistochemistry (paraffin) and ELISA.

Immunohistochemistry

WT and SSTR2 KO mice pancreatic tissue.

1:100 dilution.

Nikon ECLIPSE Ti microscope.