This is a knockout-validated antibody summary, based on the publication "SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

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Figure 1. Western blotting of SREBP1 in liver from SREBP1c+/+ mice injected with Ad-MOCK and in SREBP1c-/- mice injected with either Ad-MOCK or Ad-CRY1. From [1].

Mouse monoclonal IgG1

Company: BD Biosciences

Antibody: SREBP1

Catalog number: 557036

Summary: Mouse monoclonal IgG1, κ against human SREBP-1 aa. 301-407. Reacts with human and hamster. Suitable for western blot and immunoprecipitation.

Western blot

Liver extracts from SREBP1c+/+ and SREBP1c-/- mice.

1:1,000 dilution.

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.