This is a knockout-validated antibody summary, based on the publications "Structure and Degradation of Circular RNAs Regulate PKR Activation in Innate Immunity", as cited below [1] and "The multi-functional reovirus Ï3 protein is a virulence factor that suppresses stress granule formation and is associated with myocardial injury" for western blot knockout validation (figure 6c) [2]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).
Rabbit monoclonal IgG
Company: Abcam
Antibody: RNase L
Catalog number: ab191392
Summary: Rabbit monoclonal IgG against recombinant fragment within human RNase L (aa 550 to the C-terminus). Reacts with human by western blot.
Western blot
WT and RNase L knockout cells.
Anti-rabbit-IgG-HRP (Santa Cruz, Cat# sc-2004).
Generation of RNase L knockout (KO) HeLa cell lines by CRISPR/Cas9, confirmed by western blotting (WB). Please see Figure 1f in the article [1].
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