Phospho-MLKL antibody | knockout validation | Abcam ab196436
DOI
//dx.doi.org/10.13070/ko.en.7.1933
Date
2017-01-13

This is a knockout-validated antibody summary, based on the publication "Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Antibody information

Rabbit monoclonal

Company: Abcam

Antibody: Phospho-MLKL (phospho-S345)

Catalog number: Ab196436

Summary: Rabbit monoclonal antibody raised against a proprietary synthetic peptide sequence around phosphor-Ser345 of mouse MLKL.

Supplier recommended for WB, IP and dot blot.

Reacts with mouse phospho-MLKL.

Validation Method

Immunohistochemistry

Sample

Formalin-fixed liver sections from wild-type and MLKL knockout mice.

Primary incubation

Anti-phospho-MLKL antibody.

Figure

See Figure 1 in [1].

Disclaimer

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.

References
  1. Roychowdhury S, McCullough R, Sanz-Garcia C, Saikia P, Alkhouri N, Matloob A, et al. Receptor interacting protein 3 protects mice from high fat diet-induced liver injury. Hepatology. 2016;: pubmed publisher