Pellino 1 antibody | knockout validation

Pellino 1 antibody | knockout validation | Abcam ab199336

This is a knockout-validated antibody summary, based on the publication "PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Antibody information

Rabbit monoclonal IgG

Company: Abcam

Antibody: Pellino 1

Catalog number: ab199336

Summary: Rabbit monoclonal IgG against recombinant full length human Pellino 1 protein. Reacts with human, mouse and rat. Suitable for western blot, immunoprecipitation, and immunocytochemistry/immunofluorescence.

Validation Method

Western blot

Sample

WT and Peli1−/− MEFs.

Figure

Western blot of PELI1 and Tubulin in WT and Peli1−/− MEFs. Please see Figure 1e in the article [1].

References

Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar A, et al. PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP.. Proc Natl Acad Sci U S A. 2017;114:11944-11949 pubmed publisher

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