PINK1 antibody | knockout validation

PINK1 antibody | knockout validation | Cell Signaling 6946

This is a knockout-validated antibody summary, based on the publication "BRCA1 degradation in response to mitochondrial damage in breast cancer cells", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

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PINK1 antibody | knockout validation | Cell Signaling 6946 figure 1

Figure 1. PINK1 knockout MCF7 cells or control cells were treated with ±10 μM CCCP for 24 h. From [1].

Antibody information

Rabbit monoclonal IgG

Company: Cell Signaling

Antibody: PINK1

Catalog number: 6946

Summary: Rabbit monoclonal antibody against a synthetic peptide corresponding to residues surrounding Pro140 of human PINK1 protein. Reacts with human. Suitable for western blot and immunoprecipitation.

Validation Method

Western blot

Sample

Control and PINK1 knockout MCF7 cells.

References

Miyahara K, Takano N, Yamada Y, Kazama H, Tokuhisa M, Hino H, et al. BRCA1 degradation in response to mitochondrial damage in breast cancer cells. Sci Rep. 2021;11:8735 pubmed publisher

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