PERK antibody | knockout validation

PERK antibody | knockout validation | Cell Signaling 3192

This is a knockout-validated antibody summary, based on the publication "Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits", as cited below [1] and "MARK2 phosphorylates eIF2Î± in response to proteotoxic stress" for western blot knockout validation (figure 2b) [2]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Antibody information

Rabbit monoclonal

Company: Cell Signaling

Antibody: PERK

Catalog number: 3192

Summary: PERK (C33E10) Rabbit mAb detects endogenous levels of total PERK protein. Reactive against human, mouse, rat, and monkey

Validation Method

Western blot

Figure

Please see figure 3c of the article [1].

References

Ma T, Trinh M, Wexler A, Bourbon C, Gatti E, Pierre P, et al. Suppression of eIF2? kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci. 2013;16:1299-305 pubmed publisher
Lu Y, Kavianpour S, Zhang T, Zhang X, Nguyen D, Thombre R, et al. MARK2 phosphorylates eIF2α in response to proteotoxic stress. PLoS Biol. 2021;19:e3001096 pubmed publisher

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