PBRM1/BAF180 antibody | knockout validation | Cell Signaling 91894

This is a knockout-validated antibody summary, based on the publication "PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

PBRM1/BAF180 antibody | knockout validation | Cell Signaling 91894 figure 1
Figure 1. Pbrm1 knockout validation in Renca cells by western blot. Renca cells were treated with or without 1 ng/ml IFNγ for 8 h. From [1].
Antibody information

Rabbit monoclonal IgG

Company: Cell Signaling

Antibody: PBRM1/BAF180

Catalog number: 91894

Summary: Rabbit monoclonal antibody against a synthetic peptide corresponding to residues surrounding Leu207 of human PBRM1 protein. Reacts with human, mouse, rat and monkey. Suitable for western blot and immunoprecipitation.

Validation Method

Western blot

Sample

Control and Pbrm1-KO Renca cells.

References
  1. Liu X, Kong W, Peterson C, McGrail D, Hoang A, Zhang X, et al. PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma. Nat Commun. 2020;11:2135 pubmed publisher