P Glycoprotein antibody | knockout validation | Abcam ab170904

This is a knockout-validated antibody summary, based on the publication "P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain Injury", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

P Glycoprotein antibody | knockout validation | Abcam ab170904 figure 1
Figure 1. Antibody validation in wild-type animals via WB. From [1].
Antibody information

Rabbit monoclonal IgG

Company: Abcam

Antibody: P Glycoprotein

Catalog number: ab170904

Summary: Rabbit monoclonal antibody against a recombinant fragment within human P Glycoprotein (aa 350-750). Reacts with mouse, rat, and human. Suitable for western blot and immunohistochemistry (paraffin). Unsuitable for immunocytochemistry.

Validation Method

Western blot | Immunohistochemistry

Sample

WT and Pgp-KO mouse brain tissues.

References
  1. Vita S, Redell J, Maynard M, Zhao J, Grill R, Dash P, et al. P-glycoprotein Expression Is Upregulated in a Pre-Clinical Model of Traumatic Brain Injury. Neurotrauma Rep. 2020;1:207-217 pubmed publisher