This is a knockout-validated antibody summary, based on the publication "Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Mouse monoclonal IgG1

Company: BD Bioscience

Antibody: Munc18-1

Catalog number: 610336

Summary: Mouse monoclonal IgG1 against rat Munc-18-1 aa. 381-567. Reacts with rat, mouse and human. Suitable for western blot, immunofluorescence, immunohistochemistry and immunoprecipitation.

Western blot

WT and Munc18-1 knockout PC12 cells. Cells were lysed with 1% Triton X-100.

Please see Figure 2b in the article [1].

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.