This is a knockout-validated antibody summary, based on the publication "Genetic diversity of tumors with mismatch repair deficiency influences anti-PD-1 immunotherapy response", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).
Mouse monoclonal IgG1, kappa
Company: Invitrogen
Antibody: MSH2
Catalog number: 33-7900
Summary: Mouse monoclonal IgG1, kappa against the C-terminal fragment of the human MSH2 protein. Reacts with human and mouse. Suitable for western blot, immunocytochemistry/immunofluorescence, immunohistochemistry, and immunoprecipitation.
Western blot
WT and Msh2-knockout CT26 mouse cell lines.
Western immunoblot depicting actin control and wild type MSH2 protein (99kDa) and protein level knockout in the Msh2 gene knockout CT26 colon carcinoma cell line. Please see Suppl. Figure 2a in the article [1].
The same clone (FE11) is sold as LifeSpan Biosciences LS-C354901; Abnova MAB14123; Invitrogen 33-7900; Dako M3639; EMD Millipore MABE284.
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