This is a knockout-examined antibody summary, based on the publication "Intrinsic Immunity Shapes Viral Resistance of Stem Cells", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).
This study indicates that "the reactivity of the putative IFITM2-specific antibody disappears in the double (23KO) and triple IFITM KO (KO123) but we have not proven that it is indeed IFITM2 specific (it could react with IFITM3). " (from the communication with the author).
Mouse monoclonal IgG1
Company: Proteintech
Antibody: IFITM2
Catalog number: 66137-1-Ig
Summary: Mouse monoclonal IgG1 against a fusion protein corresponding to human IFITM2. Reacts with human by western blot, flow cytometry and ELISA.
IS NOT KO VALIDATED YET.
WT and two IFITM-KO human embryonic stem cells (ESC) clones.
Analyses of IFITM family members by western blot in WT and two KO ESC clones. Please see Figure 5a in the article [1].
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
- gene