ICSBP antibody | knockout validation | Santa Cruz sc-365042

This is a knockout-validated antibody summary, based on the publication "IRF8 Is an AML-Specific Susceptibility Factor That Regulates Signaling Pathways and Proliferation of AML Cells", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

ICSBP antibody | knockout validation | Santa Cruz sc-365042 figure 1
Figure 1. Western blot of IRF8 knockout clones in MV4-11 cells, compared to wildtype (WT) and cells infected with a non-targeting CRISPR construct (Control). From [1].
Antibody information

Mouse monoclonal IgG2b κ

Company: Santa Cruz

Antibody: ICSBP

Catalog number: sc-365042

Summary: Mouse monoclonal antibody against amino acids 357-426 of human ICSBP (IRF8). Recommended for detection of ICSBP of mouse, rat and human origin by western blot, immunoprecipitation, immunofluorescence, immunohistochemistry (paraffin) and ELISA.

Validation Method

Western blot

Sample

Control and IRF8 knockout MV4-11 cells.

References
  1. Liss F, Frech M, Wang Y, Giel G, Fischer S, Simon C, et al. IRF8 Is an AML-Specific Susceptibility Factor That Regulates Signaling Pathways and Proliferation of AML Cells. Cancers (Basel). 2021;13: pubmed publisher