This is a knockout-validated antibody summary, based on the publication "Therapeutic inducers of the HSP70/HSP110 protect mice against traumatic brain injury", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Figure 1. From figure 1 in [1]. Western blot of cortex lysates from wild-type and Hsp110 knockout mice probed with anti-Hsp105 antibody. Actin serves as a loading control.

Goat polyclonal

Company: Santa Cruz Biotechnology

Antibody: Hsp105

Catalog number: sc-1804

Summary: Goat polyclonal antibody raised against an epitope corresponding to the N-terminal region of mouse Hsp105. Supplier recommended for WB, IF and elisa. Reacts with human, mouse, rat, dog, cow, pig and bird Hsp105.

Note: this antibody will be discontinued December 15, 2016.

Western blot

Lysates of brain cortex from wild-type and Hsp110 knockout mice.

Anti-Hsp105 diluted 1:1000.

NIH Image J 1.47v software.

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.