This is a knockout-validated antibody summary, based on the publication "Fine-Tuning of the RIG-I-Like Receptor/Interferon Regulatory Factor 3-Dependent Antiviral Innate Immune Response by the Glycogen Synthase Kinase 3/β-Catenin Pathway", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).
Rabbit polyclonal
Company: Cell Signaling Technology
Antibody: GSK-3α
Catalog number: 9338
Summary: Rabbit polyclonal antibody raised against a synthetic peptide based on the human GSK-3α sequence.
Supplier recommended for WB.
Peptide affinity-purified.
Reacts with human, mouse rat and monkey GSK-3α. Detects total GSK-3α.
Western blot
Mouse embryonic fibroblasts from wild-type, GSK-3α knockout and GSK-3α / GSK-3β double knockout animals.
Anti-GSK-3α antibody.
HRP-conjugated secondary antibody (KPL).
West Lightning ECL kit (Perkin Elmer).
See Figure 1 from [1].
If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.
- If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.
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