This is a knockout-validated antibody summary, based on the publication "Metabolic inflexibility impairs insulin secretion and results in MODY-like diabetes in triple FoxO-deficient mice", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Rabbit polyclonal

Company: Cell Signaling

Antibody: Foxo4

Catalog number: 9472

Summary: Rabbit polyclonal against a synthetic peptide corresponding to residues of human Fox04. Reacts with human, mouse, rat, and monkey by western blot.

Western blot

Islet extracts of 24-week-old db/db, WT (C57BL/6) and FoxO-KO.

Please see Figure 1b in the article [1].

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.