This is a knockout-validated antibody summary, based on the publication "The lack of functional DNMT2/TRDMT1 gene modulates cancer cell responses during drug-induced senescence", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

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Figure 1. DNMT2/TRDMT1 gene knockout in four cancer cell lines, namely HeLa cervical cancer cells, MDA-MB-231 breast cancer cells, U-2 OS osteosarcoma cells and U-251 MG glioblastoma cells. Control cells (C-NIC), DNMT2/TRDMT1 gene knockout (D-NIC cells). From [1].

Mouse monoclonal IgG2b kappa

Company: Santa Cruz

Antibody: Dnmt2

Catalog number: sc-271513

Summary: Mouse monoclonal antibody against amino acids

121-391 of human Dnmt2. Reacts with mouse, rat and

human. Suitable for western blot, immunoprecipitation, immunofluorescence, and ELISA.

Western blot

Control and DNMT2/TRDMT1 knockout HeLa, MDA-MB-231, U-2 OS and U-251 MG cell lines.