DPPII/QPP/DPP7 antibody | knockout validation

DPPII/QPP/DPP7 antibody | knockout validation | R&D Systems MAB34381

This is a knockout-validated antibody summary, based on the publication "DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Antibody information

Rat monoclonal IgG2A

Company: R&D Systems

Antibody: DPPII/QPP/DPP7

Catalog number: MAB34381

Summary: Rat monoclonal IgG2A against recombinant human DPPII/QPP/DPP7 (Gly22-Leu492). Reacts with human by western blot.

Validation Method

Western blot

Sample

Control and DPP7-KO THP-1 cells.

Figure

Confirmation of DPP7 knockout in THP-1 cells by immunoblotting. Please see Figure 2b in the article [1].

References

Okondo M, Johnson D, Sridharan R, Go E, Chui A, Wang M, et al. DPP8 and DPP9 inhibition induces pro-caspase-1-dependent monocyte and macrophage pyroptosis. Nat Chem Biol. 2017;13:46-53 pubmed publisher

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