DAP12 antibody | knockout validation | New England Biolabs 12492S

This is a knockout-validated antibody summary, based on the publication "SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

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DAP12 antibody | knockout validation | New England Biolabs 12492S figure 1

Figure 1. Western blot of DAP12 in WT and DAP12 KO macrophages. Couetesy of the Author.

Antibody information

Rabbit monoclonal IgG

Company: New England Biolabs

Antibody: DAP12

Catalog number: 12492S

Summary: Rabbit monoclonal IgG against a synthetic peptide corresponding to residues near the carboxy terminus of human DAP12 protein. Reacts with human and mouse, and it is predicted to react base on 100% homology with monkey, bovine and dog. Suitable for western blot and immunoprecipitation.

Validation Method

Western blot

Sample

WT and DAP12 KO murine macrophages.

References

Chen J, Zhong M, Guo H, Davidson D, Mishel S, Lu Y, et al. SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin.. Nature. 2017;544:493-497 pubmed publisher

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