Caspase-6/CASP-6 antibody | knockout validation | Abcam ab185645

This is a knockout-validated antibody summary, based on the publication "Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Caspase-6/CASP-6 antibody | knockout validation | Abcam ab185645 figure 1
Figure 1. WT and casp6 knockout HeLa cells were mock treated or infected with VSV at an MOI of 1. Cells were harvested at 18 hpi and detected by immunoblot analysis with anti-DDX21, anti-caspase-6, anti-VSV-G, or anti-β-actin antibody. From [1].
Antibody information

Rabbit monoclonal IgG

Company: Abcam

Antibody: Caspase-6/CASP-6

Catalog number: ab185645

Summary: Rabbit monoclonal antibody against a synthetic peptide of Caspase-6. Reacts with human, mouse and rat. Suitable for western blot, immunohistochemistry (paraffin), immunoprecipitation and immunocytochemistry/immunofluorescence.

Validation Method

Western blot

Sample

WT and casp6 knockout HeLa cells.

References
  1. Wu W, Qu Y, Yu S, Wang S, Yin Y, Liu Q, et al. Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity. MBio. 2021;12:e0100521 pubmed publisher