This is a knockout-validated antibody summary, based on the publication "TNF superfamily receptor OX40 triggers invariant NKT cell pyroptosis and liver injury", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).
Rabbit monoclonal IgG
Company: Abcam
Antibody: Caspase-1
Catalog number: ab108362
Summary: Rabbit monoclonal IgG against a recombinant fragment corresponding to human Caspase-1 (aa 250 to the C-terminus). Reacts with rat and human. Suitable for western blot and immunohistochemistry (paraffin). Unsuitable for immunoprecipitation or immunocytochemistry.
Western blot
Invariant natural killer T (iNKT) cells from WT B6 and caspase 1–KO mice.
Anti-rabbit IgG HRP-linked (Cell Signaling Technology, 7074).
ECL Plus Western blotting detection system.
Western blot of the indicated proteins in FACS-sorted iNKT cells from WT B6 mice and caspase 1–KO mice stimulated with OX86 for 24 hours. Please see Figure 3e in the article [1].
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