This is a knockout-validated antibody summary, based on the publication "Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

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Figure 1. From figure 2 in [1]. Western blot of heart lysates from wild-type and CLPP knockout mice (and from DARS2 / CLPP double knockout mice). Blots probed with anti-CLPP antibody. CTRL represents a loading control.

Mouse monoclonal

Company: Sigma-Aldrich

Antibody: CLPP

Catalog number: WH0008182-M1 (Clone 300)

Summary: Mouse monoclonal antibody raised against a GST fusion protein containing residues 178-278 of human CLPP. Supplier recommended for WB and elisa. Reacts with human, mouse and rat CLPP.

Western blot

Heart extracts of wild-type and CLPP knockout mice.

Anti-CLPP antibody diluted 1:1000.

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.