CIZ1 antibody | knockout validation | Abcam ab172442
DOI
//dx.doi.org/10.13070/ko.en.6.1852
Date
2016-11-23

This is a knockout-validated antibody summary, based on the publication " Motor phenotypes and molecular networks associated with germline deficiency of Ciz1", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

Antibody information

Mouse polyclonal

Company: Abcam

Antibody: CIZ1 (CDKN1A interacting zinc finger protein 1)

Catalog number: Ab172442

Summary: Mouse polyclonal antibody raised against full-length recombinant human CIZ1. Supplier recommended for WB. Protein A purified. Reacts with human CIZ1.

Validation Method

Western blot (with initial immunoprecipitation step)

Sample

Lysates of mouse brain cerebellum and cerebral cortex immunoprecipitated with anti-CIZ1 antibody.

Blocking agent

5% milk powder.

Primary incubation

Anti-CIZ1 diluted 1:10000.

Secondary incubation

HRP-conjugated goat anti-rabbit IgG (Jackson ImmunoResearch Labs).

Detection

ECL reagent (Amersham).

Figure

See figure 3 in [1].

Disclaimer

If the antibody described in this summary is a polyclonal antibody, since polyclonal antibodies are of limited quantity, please inquire the supplier whether any current polyclonal antibody with the same catalog number is exactly the same as the one described in this summary. Sometimes, different bleeds or different animals are used, usually with a different lot number. In such cases, the result in this summary may not apply to the new antibody with the same catalog number.

References
  1. Xiao J, Vemula S, Xue Y, Khan M, Kuruvilla K, Marquez-Lona E, et al. Motor phenotypes and molecular networks associated with germline deficiency of Ciz1. Exp Neurol. 2016;283:110-120 pubmed publisher