CD105 antibody | knockout validation

CD105 antibody | knockout validation | Abcam ab169545

This is a knockout-validated antibody summary, based on the publication "Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells", as cited below [1]. Labome curates formal publications to compile a list of antibodies with unambiguous specificity within Validated Antibody Database (VAD).

[enlarge]

CD105 antibody | knockout validation | Abcam ab169545 figure 1

Figure 1. Protein level of CD105, NANOG, C-MYC and CDA were examined by western blot after CRISPR/Cas9 mediated CD105 knockout in ACHN-CD105(+) cells. From [1].

Antibody information

Rabbit monoclonal IgG

Company: Abcam / Epitomics

Antibody: CD105

Catalog number: ab169545

Summary: Rabbit monoclonal IgG against a recombinant fragment corresponding to human CD105 (aa 1-200). Reacts with human. Suitable for western blot and immunohistochemistry (paraffin).

Validation Method

Western blot

Sample

Control and CD105 knockout ACHN cells.

References

Hu J, Guan W, Liu P, Dai J, Tang K, Xiao H, et al. Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells. Stem Cell Reports. 2017;9:464-477 pubmed publisher

contribute

If you are aware of any publication with knockout studies validating a monoclonal or recombinant antibody, either purchased from a supplier or developed by the author(s), please notify us through feedback.