Overview

Labome lists 613107 antibody products against 63138 genes, including 19157 human, 15864 mouse, and 14209 rat genes.

Labome antibody review database lists 42704 antibody applications for 8036 genes, based on 9666 formal publications. see examples: beta actin antibody, GFP antibody, HA antibody, phosphotyrosine antibody, polyhistidine antibody, and Myc antibody.

other brands: Babco, Signet, Sternberger Monoclonals, Senetek

Gene Overview
Labome antibody review database contains antibody applications for 190 genes with antibodies supplied from Covance based on 323 formal publications.
Select Gene Review
Here are the reagent applications for a select list of genes from Labome database .
  • human APP gene: 24 publications, see all APP antibody reviews
    • Signet 6E10 monoclonal antibody specific for beta-amyloid peptide 1-17 was used in western blot to study the characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms produced by alternative splicing of the RNA.
    • Senetek monoclonal amyloid beta antibody 4G8 was used in immunoprecipitation to study the biological function of presenilin-1 maturation.
    • Signet amyloid beta-protein antibody was used in immunohistochemistry to study the muscle protein dysferlin accumulates in the Alzheimer brain.
    • Senetik anti-amyloid beta antibody 6E10 was used in frozen brain sections from mice and in immunohistochemistry to study the characterization of transgenic mouse lines co-expressing mutant human presenilin 1 and amyloid precursor proteins.
    • Signet Laboratories monoclonal anti-Abeta antibody 6E10 was used in immunoprecipitation to study the effect of E693deletemutation in amyloid precursor protein on intracellular accumulation of amyloid beta oligomers and its role in causing endoplasmic reticulum stress-induced apoptosis in cultured cells
  • human RNA polymerase II gene: 16 publications, see all RNA polymerase II antibody reviews
    • Covance Research Products anti-phosphorylated RNA Polymerase II (clone CTD4H8) was used in ChIP assay to study ERBB2 gene expression in mammary cancer cells
    • Covance anti-Rpb1 antibody was used to assay carry out chromatin immunoprecipitation assays in order to investigate the role for Hog1-mediated recruitment of RSC complex in nucleosome organization of stress-responsive loci.
    • Covance antibody against RNAPII phosphorylated at serines 2 and 5 (8WG16) was used in ChIP assays to study aryl hydrocarbon receptor-mediated transcription in MCF-7 human breast carcinoma, T47D breast carcinoma cells, and HuH7 human liver carcinoma cells.
    • Covance mouse anti-RNA Pol II antibody (clones H14, H5, 8WG16) was used to perform immunoprecipitation in order to study the elongation funtion of RNA Polymerase II during co-transcriptional splicing.
    • Covance anti-RNA polymerase II antibody was used to perform ChIP assays in order to study the association between the papillomavirus E2 proteins, the host Brd4 protein and the transcriptionally active cellular genes.
  • mouse K14 gene: 14 publications, see all K14 antibody reviews
    • Babco anti-murine K14 antibody was used in cryostat sections from mouse dorsal skin and of ileum and in immunohistochemistry to study the role of T1alpha/podoplanin in vascular development and the effects of gene disruption in mice.
    • Covance anti-K14 antibody was used to perform immunohistochemistry in order to show that DEK overexpression can disrupt the normal epithelial differentiation.
    • Covance rabbit anti-mouse-K14 antibody was used in immunohistochemistry to study the role for the effect of TERT on a Myc- and Wnt-related developmental program in epithelial proliferation in paraffin sections from mice dorsal skin.
    • Covance Laboratories anti-keratin 14 antibody was used in immunohistochemistry in order to study the role of Smad4 in follicle stem cell maintenance.
    • Covance Research Products anti-keratin 14 antibody was used to perform immunohistochemistry in order to study the influence of the overexpression of transcription factor sp2 on epidermal differentiation and tumorigenesis.
  • mouse Krt5 gene: 12 publications, see all Krt5 antibody reviews
    • Covance Research polyclonal anti-mouse keratin 5 (K5) was used in immunohistochemistry to detect keratin 5 in mouse Ikaros null embryos and thymi of adult mice.
    • Covance rabbit polyclonal keratin 5 antibody was used in western blot (1:10000) and immunohistochemistry (1:1000, 1:2000) in order to demonstrate C/EBPalpha and C/EBPbeta are essential for sebocyte differentiation and epidermal squamous differentiation in adult mouse skin.
    • Covance anti-keratin 5 antibody was used in immunohistochemistry in order to demonstrate that BIM is required for caspase-dependent cell death in the mammary gland and that in the absence of primary death mechanisms, such as apoptosis, alternative clearance mechanisms contribute to proper lumen formation in the mammary gland in vivo.
    • Covance anti-keratin 5 antibody was used in immunohistochemistry to study the role of AGF in epidermal keratinocytes.
    • Covance Research Products anti-keratin 5 antibody was used to perform immunohistochemistry in order to study the influence of the overexpression of transcription factor sp2 on epidermal differentiation and tumorigenesis.
  • human TUBB3 gene: 10 publications, see all TUBB3 antibody reviews
    • Covance rabbit anti-betaIII-tubulin was used in immunocytochemistry to study the regulation of the intracellular trafficking of Reelin receptors by Disabled1
    • Covance polyclonal rabbit anti-Class III beta-tubulin (TUJ1) antibody (PRB435P) was used in immunohistochemistry to study what happens in the cerebellar cortex of peripuberal rabbits by using endogenous and exogenously-administered cell proliferation antigens in association with a cohort of typical markers for neurogenesis.
    • Covance rabbit anti-acetylated Class III beta-Tubulin antibody was used in immunohistochemistry in order to study the role of Vsx2 in mediating mitogen signaling
    • Covance mouse anti-beta III tubulin antibody was used for western blot in order to investigate the role of Neuropilin 1 in the regulation of neural crest cells specification.
    • Covance beta-tubulin III antibody (1:1,000) was used in immunohistochemistry to identify SOX2 as a universal neural stem cell marker.
  • mouse Tubb3 gene: 10 publications, see all Tubb3 antibody reviews
    • Covance rabbit anti-TuJ1 antibody was used to carry out immunofluorescence assays in order to investigate the role for Dnmt3a in the regulation of neurogenic genes transcription and neural development by methylating gene intergenic regions.
    • Covance mouse monoclonal anti-Tuj1 conjugated to Alexa-488 was used at 1:2000 to perform immunohistochemistry in order to show that mammalian cerebral cortex contains fate-restricted neural progenitors.
    • Covance anti-betaIII tubulin was used to perform immunohistochemistry in order to study the function of septate junction protein caspr.
    • Covance mouse anti-Tuj-1 antibody was used to perform immunocytochemistry in order to study the regulation of neurofibromatosis-1 to neuroglial progenitor proliferation and glial differentiation.
    • Babco beta-tubulin III antibody (Tuj1) was used in immunohistochemistry to study the molecular function of ATM in the developing nervous system.
  • mouse K10 gene: 8 publications, see all K10 antibody reviews
    • Covance Research Products anti-keratin 10 antibody was used to perform immunohistochemistry in order to study the influence of the overexpression of transcription factor sp2 on epidermal differentiation and tumorigenesis.
    • Covance rabbit polyclonal keratin 14 antibody was used in western blot (1:10000) in order to demonstrate C/EBPalpha and C/EBPbeta are essential for sebocyte differentiation and epidermal squamous differentiation in adult mouse skin.
    • Covance rabbit polyclonal keratin 10 antibody was used in western blot (1:10000) and immunohistochemistry (1:1000, 1:2000) in order to demonstrate C/EBPalpha and C/EBPbeta are essential for sebocyte differentiation and epidermal squamous differentiation in adult mouse skin.
    • Covance anti-K10 antibody was used to perform immunohistochemistry in order to show that DEK overexpression can disrupt the normal epithelial differentiation.
    • Covance Research Products K10 antibody was used in ChIP assays in order to identify p63 as a key regulatory molecule during palate development and study the mechanism for the cooperative role of p63 and IRF6 in orofacial development in mice and humans.
  • human c-Myc gene: 7 publications, see all c-Myc antibody reviews
    • Covance anti-myc antibody was used to perform western blot in order to study the roles of Norbin during the metabotropic glutamate receptor 5 signaling.
    • Covance Myc antibody was used to perform Western blots in order to show the role of Wrch-1 in disruption of TJs and actin organization.
    • Covance anti-c-Myc Ab was used to detect c-Myc in Western blots in order to find out the novel mechanism by which eIF4E levels are regulated at the level of mRNA stability.
    • Covance anti-Myc antibody was used to perform Western blots in order to study the roles of the iron-regulated ubiquitin ligase in the regulation towards the iron homeostasis.
    • Covance Myc antibody was used in immunocytochemistry in order to demonstrate that huntington's disease protein contributes to RNA-mediated gene silencing.