Glycogen Synthase | US Biological G8170-18D product information

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product summary

company name :

US Biological

product type :

antibody

product name :

Glycogen Synthase

catalog :

G8170-18D

quantity :

100 ul

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

7H22(15B1)

reactivity :

human

product information

Catalog Number :

G8170-18D

Product wo Prefix :

Glycogen Synthase

Host :

rabbit

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

7H22(15B1)

Isotype :

IgG

Desc1 :

Glycogen synthase (GS) is a key enzyme in the regulation of glycogen synthesis. There are two main isoforms of mammalian GS: the muscle isoenzyme and the liver form. Muscle GS is expressed in several tissues, and liver GS appears to be tissue specific. GS is regulated by multi-site phosphorylation and by the binding of allosteric ligands. Phosphorylation leads to inactivation of GS, but activity is restored by the binding of the allosteric activator glucose-6-phosphate, which induces its dephosphorylation and activation Applications: Suitable for use in ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. Immunoprecipitation: 1:25 Immunohistochemistry (Paraffin): 1:100. Use citrate as unmasking buffer. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo Rt

Immunogen :

Synthetic peptide derived from the sequence of human glycogen synthase.

Specificity :

Recognizes endogenous levels of total human muscle and liver glycogen synthase protein. Species Crossreactivity: mouse and rat

Purity :

Purified

Form :

Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol.

Concentration :

Not Determined

Desc2 :

Product Type: Mab Isotype: IgG Clone No: 7H22(15B1) Host: rabbit Source: human Concentration: Not Determined Form: Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol. Purity: Purified Immunogen: Synthetic peptide derived from the sequence of human glycogen synthase. Specificity: Recognizes endogenous levels of total human muscle and liver glycogen synthase protein. Species Crossreactivity: mouse and rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC IP WB

Storage Temperature :

-20°C

Reference :

1. Browner, M.F. et al. (1989) Proc. Natl. Acad. Sci. USA 86, 1443-1447. 2 Bai, G. et al. (1990) J. Biol. Chem. 265, 7843-7848. 3. Roach, P.J. et al. (1998) J. Basic Clin. Physiol. Pharmacol. 9, 139-151. 4 Villar-Palasi, C. and Guinovart, J.J. (1997) FASEB J.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/13/G8170-18D_1.jpg