ZM 306416 hydrochloride | Tocris Bioscience 2499/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ZM 306416 hydrochloride

catalog :

2499/10

quantity :

10 mg

price :

209 USD

citations: 2

Reference
Crouch E, Liu C, Silva Vargas V, Doetsch F. Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage. J Neurosci. 2015;35:4528-39 pubmed publisher
Yuan X, Eng G, Arkonac D, Chao P, Vunjak Novakovic G. Endothelial cells enhance the migration of bovine meniscus cells. Arthritis Rheumatol. 2015;67:182-92 pubmed publisher

product information

CHEMISTRY :

Cl.COC1=C(OC)C=C2C(NC3=CC=C(Cl)C=C3F)=NC=NC2=C1

Stock Reference :

2499/10

Cat Number :

2499

Product Name :

ZM 306416 hydrochloride

Cas Number :

[196603-47-1]

Unit Size :

10 mg

Size :

Unit :

USD :

209 USD

Primary Category :

Enzyme-Linked Receptors

Secondary Category :

Receptor Tyrosine Kinases (RTKs)

Tertiary Category :

VEGFR

Primary Action :

Inhibitor of VEGF receptor tyrosine kinase

Biological Description :

Inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. Inhibits activity of KDR and FLT VEGF receptors (IC50 values are 100 nM and 2 muM respectively) and displays > 3-fold selectivity over FGFR-1. Orally active in vivo.

Storage :

Desiccate at RT

Formula :

C16H13N3O2FCl.HCl

Molwt :

370.21

Minimum Purity :

> 99%

Solubility :

Soluble to 10 mM in DMSO

RTECS No :

Not available

Public Caveats :

Sold with the permission of AstraZeneca UK Ltd.