LOE 908 hydrochloride | Tocris Bioscience 2314/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LOE 908 hydrochloride

catalog :

2314/10

quantity :

10 mg

price :

191 USD

citations: 2

Reference
Varadarajan S, Tanaka K, Smalley J, Bampton E, Pellecchia M, Dinsdale D, et al. Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis. PLoS ONE. 2013;8:e56603 pubmed publisher
Harper M, Poole A. Protein kinase Ctheta negatively regulates store-independent Ca2+ entry and phosphatidylserine exposure downstream of glycoprotein VI in platelets. J Biol Chem. 2010;285:19865-73 pubmed publisher

product information

brand :

Tocris

master code :

2314

SKU :

2314/10

product name :

LOE 908 hydrochloride

unit size :

10 mg

description :

Potent H3 agonist, highly selective over H4

target :

Ion Channel Modulators

category :

Small Molecules

purity :

98%

storage :

Desiccate at RT

observed molecular weight :

749.29

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

LOE 908 hydrochloride is a broad spectrum cation channel blocker. Inhibits several cation channels including store-operated calcium channels (SOCs), voltage-operated calcium channels (VOCs), non-selective cation channels (NSCCs), AMPA, NMDA, Na+ and K+ channels. Neuroprotective; reduces cortical infarct size and improves neurological outcome following middle cerebral artery occlusion.

extended description :

Broad spectrum cation channel blocker; neuroprotective

chemical name text :

3,4-Dihydro-6,7-dimethoxy- -phenyl-N,N-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamide hydrochloride

formula :

C 41 H 48 N 2 O 9 .HCl

formula text :

C41H48N2O9.HCl

cas num :

143482-60-4

USD :

178

Jul-22 :

191 USD

product details :

Broad spectrum cation channel blocker; neuroprotective

sizes available :

10 mg (also 50 mg)