AMPD1 Polyclonal Antibody | Invitrogen PA5-23173 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

AMPD1 Polyclonal Antibody

catalog :

PA5-23173

quantity :

100 µg

price :

375 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

AMPD1 Polyclonal Antibody

Catalog # :

PA5-23173

Quantity :

100 µg

Price :

375 USD

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Non-human primate, Rat

Applications :

Immunohistochemistry (Paraffin): 5-10 µg/mL, Western Blot: 0.5-2 µg/mL

Species :

Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

AMP deaminase (AMPD) is an allosteric enzyme involved in the regulation of adenosine metabolism. It catalyzes a central reaction in purine nucleotide biosynthesis where AMP is deaminated to IMP, liberating ammonia. There are three functional isoforms of AMPD. AMPD1 (E.C. No 3.5.4.6.) is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. This protein is the predominant member of AMPD multi-gene family and is considered as the sensor of the cell’s changing energy requirements. AMPD1 deficiency causes irregular muscle metabolism due to lower rate of ATP degradation, phosphocreatine hydrolysis and accumulation of lactic acid. Mutated AMPD1 expression has been detected in neuromuscular disorders, exercise-induced skeletal muscle myopathies and congestive heart failures due to coronary artery diseases.

Immunogen :

Synthetic peptide (506 MFSSKSPKPQEWTLEKN 522) of AMPDA1 protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 5-10 µg/mL, Western Blot: 0.5-2 µg/mL

Aliases :

adenosine monophosphate deaminase 1; adenosine monophosphate deaminase 1 (isoform M); adenosine monophosphate deaminase-1 (muscle); AI553520; AMP deaminase 1; AMP deaminase isoform M; AMPD; Ampd01; Ampd1; Ampd-1; MAD; MADA; MMDD; myoadenylate deaminase; RATAMPD01; RP5-1000E10.1; skeletal muscle AMPD