PKC beta-1,2 Polyclonal Antibody | Invitrogen PA5-13740 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PKC beta-1,2 Polyclonal Antibody

catalog :

PA5-13740

quantity :

400µL

price :

US 330.00

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

product information

Product Type :

Antibody

Product Name :

PKC beta-1,2 Polyclonal Antibody

Catalog # :

PA5-13740

Quantity :

400µL

Price :

US 330.00

Clonality :

Polyclonal

Purity :

Protein G

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry: 1:25, Western Blot: 1:1000

Species :

Human

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC beta is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Isoform 1 uses an alternate exon at the 3' end compared to isoform 2, which includes a part of the coding region. The resulting isoform 1 has a distinct and shorter C-terminus, as compared to isoform 2.

Immunogen :

KLH conjugated synthetic peptide between 303-334 amino acids from the central region of human PKC beta1/2

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry: 1:25, Western Blot: 1:1000

Aliases :

Protein kinase C, beta type; PRKCB1; PRKCB; PKCB