This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
c-Cbl Polyclonal Antibody
catalog :
PA5-11355
quantity :
400µL
price :
US 330.00
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry
product information
Product Type :
Antibody
Product Name :
c-Cbl Polyclonal Antibody
Catalog # :
PA5-11355
Quantity :
400µL
Price :
US 330.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
Species :
Human
Isotype :
IgG
Storage :
-20° C, Avoid Freeze/Thaw Cycles
Description :
CBLC proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.
Immunogen :
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CBLC
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry: 1:50-1:100, Western Blot: 1:1000
Aliases :
Signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3; RING finger protein 57; RNF57; CBLC
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA