Notch1 Monoclonal Antibody (F.981.3) | Invitrogen MA5-14799 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon

product type :

antibody

product name :

Notch1 Monoclonal Antibody (F.981.3)

catalog :

MA5-14799

quantity :

100 ul

price :

US 261

clonality :

monoclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot

product information

Product Type :

MA5-14799

Product Name :

Notch1 Monoclonal Antibody (F.981.3)

Catalog # :

MA5-14799

Quantity :

100 ul

Price :

US 261

Clonality :

Monoclonal

Purity :

Affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot

Species :

Hu, Ms, Rt

Clone :

F.981.3

Gene Identification :

Entrez: 4851, 18128, 25496; Uniprot: P46531, Q01705

Isotype :

IgG

Storage :

-20°C

Description :

This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development.

Immunogen :

Synthetic peptide corresponding to residues surrounding Pro2439 of human Notch1

Format :

Liquid; 0.01 M HEPES, 100 µg/ml BSA, 50 % glycerol, 0.15 M NaCl, <0.02 % sodium azide

Applications w/Dilutions :

WB 1:1000

Aliases :

Notch homolog 1, translocation-associated; neurogenic locus notch homolog protein 1; translocation-associated notch protein TAN-1