Surfactant Protein B (Mature) Monoclonal Antibody (SPB02 (1B9)) | Invitrogen MA5-11889 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon

product type :

antibody

product name :

Surfactant Protein B (Mature) Monoclonal Antibody (SPB02 (1B9))

catalog :

MA5-11889

quantity :

500 ul

price :

US 349

clonality :

monoclonal

host :

mouse

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

MA5-11889

Product Name :

Surfactant Protein B (Mature) Monoclonal Antibody (SPB02 (1B9))

Catalog # :

MA5-11889

Quantity :

500 ul

Price :

US 349

Clonality :

Monoclonal

Purity :

protein A

Host :

Mouse

Reactivity :

Human

Applications :

Immunofluorescence and Immunohistochemistry (Paraffin)

Species :

Clone :

SPB02 (1B9)

Gene Identification :

Entrez: 6439; Uniprot: P07988

Isotype :

IgG2a, kappa

Storage :

4° C

Description :

ProSP-B is glycosylated in the Golgi apparatus and undergoes carboxy- and amino-terminal proteolysis by a cathepsin D-like protease. Pulmonary surfactant is a complex mixture of phospholipids and proteins that is secreted from type II cells in alveoli and reduces the surface tension at the alveolar air-liquid interface, providing alveolar stability necessary for normal ventillation. Four distinct proteins isolated from pulmonary surfactant are termed surfactant proteins A, B, C, and D. SP-A (28-36kDa) and SP-D (43kDa) are collagenous carbohydrate-binding proteins, whereas SP-B (8-9kDa) and SP-C (4kDa) are non-collagenous hydrophobic proteins. SP-B is expressed in pulmonary adenocarcinomas with acinar, papillary, bronchioloalveolar, and solid growth patterns. Squamous cell and large cell carcinomas of the lung and nonpulmonary adenocarcinomas do not express SP-B.

Immunogen :

Recombinant surfactant protein B

Format :

Liquid; PBS with 0.2 % BSA, 0.09 % sodium azide

Applications w/Dilutions :

IF Assay Dependent, IHC (P) 1-2 µg/ml

Aliases :

18 kDa pulmonary-surfactant protein, 6 kDa protein,pulmonary surfactant-associated protein B, pulmonary surfactant-associated proteolipid SPL(Phe)