This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon
product type :
antibody
product name :
Cdc47 Antibody (47DC141)
catalog :
MA1-91554
quantity :
1 mL
price :
US 674.00
clonality :
monoclonal
host :
mouse
reactivity :
human, mouse, rat, dog, rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 25
Published Application/Species/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 7
Pedersen M, Larsen A, Pedersen D, Stoltenberg M, Penkova M. Metallic gold treatment reduces proliferation of inflammatory cells, increases expression of VEGF and FGF, and stimulates cell proliferation in the subventricular zone following experimental traumatic brain injury. Histol Histopathol. 2009;24:573-86 pubmed
  • western blot; human; fig 4
Kliszczak A, Rainey M, Harhen B, Boisvert F, Santocanale C. DNA mediated chromatin pull-down for the study of chromatin replication. Sci Rep. 2011;1:95 pubmed publisher
de Fátima Pereira A, Mara da Costa V, Cristina Magalhães Santos M, Maciel de A Ribeiro R, Gabriela Silva A, Carmo Horta Pinto F, et al. Evaluation of the effects of methotrexate released from polymeric implants in solid Ehrlich tumor. Biomed Pharmacother. 2014;68:365-8 pubmed publisher
de Souza C, Araújo E Silva A, de Jesus Ferraciolli C, Moreira G, Campos L, Dos Reis D, et al. Combination therapy with carboplatin and thalidomide suppresses tumor growth and metastasis in 4T1 murine breast cancer model. Biomed Pharmacother. 2014;68:51-7 pubmed publisher
Broderick R, Rainey M, Santocanale C, Nasheuer H. Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage. FEBS J. 2013;280:4888-902 pubmed publisher
Souza C, Gamba C, Campos C, Lopes M, Ferreira M, Andrade S, et al. Carboplatin delays mammary cancer 4T1 growth in mice. Pathol Res Pract. 2013;209:24-9 pubmed publisher
Cladel N, Budgeon L, Hu J, Balogh K, Christensen N. Synonymous codon changes in the oncogenes of the cottontail rabbit papillomavirus lead to increased oncogenicity and immunogenicity of the virus. Virology. 2013;438:70-83 pubmed publisher
Silva J, Ocarino N, Vieira A, Nascimento E, Serakides R. Effects of hypo- and hyperthyroidism on proliferation, angiogenesis, apoptosis and expression of COX-2 in the corpus luteum of female rats. Reprod Domest Anim. 2013;48:691-8 pubmed publisher
Wiebusch L, Uecker R, Hagemeier C. Human cytomegalovirus prevents replication licensing by inhibiting MCM loading onto chromatin. EMBO Rep. 2003;4:42-6 pubmed
Peev N, Tonchev A, Penkowa M, Kalevski S, Haritonov D, Chaldakov G. Cell proliferation index predicts relapse of brain metastases in non-irradiated patients. Acta Neurochir (Wien). 2008;150:1043-8; discussion 1048 pubmed publisher
Araújo Júnior R, Silva Júnior R, Vasconcelos M, Guimarães S, Vasconcelos P, Garcia J. Preconditioning with L-alanyl-glutamine reduces hepatic ischemia-reperfusion injury in rats. Acta Cir Bras. 2011;26:8-13 pubmed
Leite E, Freitas E, Souza C, Ocarino N, Cassali G, Ferreira E, et al. [Proliferation, apoptosis and mammary gland histomorphometry of thyroxine-treated rats on lactation and after weaning and development of offspring]. Arq Bras Endocrinol Metabol. 2007;51:1000-6 pubmed
Ferreira E, da Silva A, Serakides R, Gomes M, Cassali G. Ehrlich tumor as model to study artificial hyperthyroidism influence on breast cancer. Pathol Res Pract. 2007;203:39-44 pubmed
Stelzer M, Pitot H, Liem A, Lee D, Kennedy G, Lambert P. Rapamycin inhibits anal carcinogenesis in two preclinical animal models. Cancer Prev Res (Phila). 2010;3:1542-51 pubmed publisher
Pinto F, Menezes G, Moura S, Cassali G, Teixeira M, Cara D. Induction of apoptosis in tumor cells as a mechanism of tumor growth reduction in allergic mice. Pathol Res Pract. 2009;205:559-67 pubmed publisher
Leite E, Souza C, Carvalho-Júnior A, Coelho L, Lana A, Cassali G, et al. Encapsulation of cisplatin in long-circulating and pH-sensitive liposomes improves its antitumor effect and reduces acute toxicity. Int J Nanomedicine. 2012;7:5259-69 pubmed publisher
Stappenbeck T, Gordon J. Extranuclear sequestration of phospho-Jun N-terminal kinase and distorted villi produced by activated Rac1 in the intestinal epithelium of chimeric mice. Development. 2001;128:2603-14 pubmed
Sarkisian C, Keister B, Stairs D, Boxer R, Moody S, Chodosh L. Dose-dependent oncogene-induced senescence in vivo and its evasion during mammary tumorigenesis. Nat Cell Biol. 2007;9:493-505 pubmed
Broderick R, Ramadurai S, Toth K, Togashi D, Ryder A, Langowski J, et al. Cell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy. PLoS ONE. 2012;7:e35537 pubmed publisher
Jabbar S, Abrams L, Glick A, Lambert P. Persistence of high-grade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene. Cancer Res. 2009;69:4407-14 pubmed publisher
Kingsbury S, Loddo M, Fanshawe T, Obermann E, Prevost A, Stoeber K, et al. Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells. Exp Cell Res. 2005;309:56-67 pubmed
Shen H, Sikorska M, Leblanc J, Walker P, Liu Q. Oxidative stress regulated expression of ubiquitin Carboxyl-terminal Hydrolase-L1: role in cell survival. Apoptosis. 2006;11:1049-59 pubmed
Berlato D, Stewart J, Newton R, Maglennon G, Monti P, Flindall A, et al. Evaluation of minichromosome maintenance protein 7 as a prognostic marker in canine cutaneous mast cell tumours. Vet Comp Oncol. 2012;10:135-42 pubmed publisher
Maria de Souza C, Fonseca de Carvalho L, da Silva Vieira T, Cândida Araújo E Silva A, Teresa Paz Lopes M, Alves Neves Diniz Ferreira M, et al. Thalidomide attenuates mammary cancer associated-inflammation, angiogenesis and tumor growth in mice. Biomed Pharmacother. 2012;66:491-8 pubmed publisher
Balsitis S, Dick F, Dyson N, Lambert P. Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis. Cancer Res. 2006;66:9393-400 pubmed
product information
Product Type :
Antibody
Product Name :
Cdc47 Antibody (47DC141)
Catalog # :
MA1-91554
Quantity :
1 mL
Price :
US 674.00
Clonality :
Monoclonal
Purity :
IgG fraction
Host :
Mouse
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:50-1:100, Immunoprecipitation: Assay dependent, Western Blot: Assay dependent
Species :
Human
Clone :
47DC141
Isotype :
IgG1
Storage :
4° C
Description :
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Immunogen :
BALB/C mice were injected with recombinant human CDC47 protein.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50-1:100, Immunoprecipitation: Assay dependent, Western Blot: Assay dependent
Aliases :
Cyclin dependent kinase 47
PubMed References :
11493576, 12524519, 16005865, 16544100, 17018593, 17137730, 17450133, 17934669, 18773139, 19268488, 19435895, 21149330, 21971650, 22235877, 22536402, 23091378, 23433866, 23910567, 24054045, 24529847
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
www.thermofisher.com
800-678-5599
headquarters: USA