This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon
product type :
antibody
product name :
Cyclin B1 Monoclonal Antibody (V152)
catalog :
MA1-46103
quantity :
100 µg
price :
US 292
clonality :
monoclonal
host :
mouse
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 10
Whittaker S, te Poele R, Chan F, Linardopoulos S, Walton M, Garrett M, et al. The cyclin-dependent kinase inhibitor seliciclib (R-roscovitine; CYC202) decreases the expression of mitotic control genes and prevents entry into mitosis. Cell Cycle. 2007;6:3114-31 pubmed
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Duensing A, Liu Y, Spardy N, Bartoli K, Tseng M, Kwon J, et al. RNA polymerase II transcription is required for human papillomavirus type 16 E7- and hydroxyurea-induced centriole overduplication. Oncogene. 2007;26:215-23 pubmed
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Hall J, Kow E, Nevis K, Lu C, Luce K, Zhong Q, et al. Cdc6 stability is regulated by the Huwe1 ubiquitin ligase after DNA damage. Mol Biol Cell. 2007;18:3340-50 pubmed
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Raynaud F, Whittaker S, Fischer P, McClue S, Walton M, Barrie S, et al. In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202. Clin Cancer Res. 2005;11:4875-87 pubmed
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Davy C, Jackson D, Raj K, Peh W, Southern S, Das P, et al. Human papillomavirus type 16 E1 E4-induced G2 arrest is associated with cytoplasmic retention of active Cdk1/cyclin B1 complexes. J Virol. 2005;79:3998-4011 pubmed
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Ersvaer E, Zhang J, McCormack E, Olsnes A, Anensen N, Tan E, et al. Cyclin B1 is commonly expressed in the cytoplasm of primary human acute myelogenous leukemia cells and serves as a leukemia-associated antigen associated with autoantibody response in a subset of patients. Eur J Haematol. 2007;79:210-25 pubmed
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Nakamura N, Yamamoto H, Yao T, Oda Y, Nishiyama K, Imamura M, et al. Prognostic significance of expressions of cell-cycle regulatory proteins in gastrointestinal stromal tumor and the relevance of the risk grade. Hum Pathol. 2005;36:828-37 pubmed
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product information
Product Type :
MA1-46103
Product Name :
Cyclin B1 Monoclonal Antibody (V152)
Catalog # :
MA1-46103
Quantity :
100 µg
Price :
US 292
Clonality :
Monoclonal
Purity :
Protein G
Host :
Mouse
Reactivity :
Human, Mouse
Applications :
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation and Western Blot
Species :
Hu, Ms
Clone :
V152
Gene Identification :
Entrez: 891, 268697; Uniprot: P14635, P24860
Isotype :
IgG1
Storage :
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Description :
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
Immunogen :
Hamster Cyclin B1 expressed in bacteria.
Format :
Liquid; PBS with no preservative
Applications w/Dilutions :
FACS 1:10-1:1000, WB 1-2 µg/ml, ICC 1:10-1:500, IP 1:10-1:500, IF 1:10-1:500, IHC (P) 1-2 µg/ml
Aliases :
CCNB
PubMed References :
10842190, 18075315, 19298605, 11719282, 15767402, 23520512, 16819507, 17567951, 17655707, 22870341, 10471528, 10632341, 14729633, 16000586, 16084954, 12953058
company information

Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
www.thermofisher.com81 Wyman Street
Waltham, MA USA 02451
800-678-5599
headquarters: USA
questions and comments
